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Target
Adenosine receptor A3
Ligand
BDBM50091117
Substrate
n/a
Meas. Tech.
ChEMBL_752772 (CHEMBL1798408)
Ki
551±n/a nM
Citation
 Lenzi, O; Colotta, V; Catarzi, D; Varano, F; Squarcialupi, L; Filacchioni, G; Varani, K; Vincenzi, F; Borea, PA; Ben, DD; Lambertucci, C; Cristalli, G Synthesis, structure-affinity relationships, and molecular modeling studies of novel pyrazolo[3,4-c]quinoline derivatives as adenosine receptor antagonists. Bioorg Med Chem 19:3757-68 (2011) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50091117
Synonyms:
2-Phenyl-2H-pyrazolo[3,4-c]quinolin-4-ylamine | 2-phenyl-2H-pyrazolo[3,4-c]quinolin-4-amine | CHEMBL320805
Type:
Small organic molecule
Emp. Form.:
C16H12N4
Mol. Mass.:
260.2933
SMILES:
Nc1nc2ccccc2c2cn(nc12)-c1ccccc1
Structure:
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