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Target
Transcriptional activator protein LuxR
Ligand
BDBM50266163
Substrate
n/a
Meas. Tech.
ChEMBL_765232 (CHEMBL1827785)
IC50
860±n/a nM
Citation
 Lowery, CA; Salzameda, NT; Sawada, D; Kaufmann, GF; Janda, KD Medicinal chemistry as a conduit for the modulation of quorum sensing. J Med Chem 53:7467-89 (2010) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LuxR
Synonyms:
LUXR_ALIFS | luxR
Type:
PROTEIN
Mol. Mass.:
28563.86
Organism:
Vibrio fischeri
Description:
ChEMBL_831639
Residue:
250
Sequence:
MKNINADDTYRIINKIKACRSNNDINQCLSDMTKMVHCEYYLLAIIYPHSMVKSDISILDNYPKKWRQYYDDANLIKYDPIVDYSNSNHSPINWNIFENNAVNKKSPNVIKEAKTSGLITGFSFPIHTANNGFGMLSFAHSEKDNYIDSLFLHACMNIPLIVPSLVDNYRKINIANNKSNNDLTKREKECLAWACEGKSSWDISKILGCSERTVTFHLTNAQMKLNTTNRCQSISKAILTGAIDCPYFKN
  
Inhibitor
Name:
BDBM50266163
Synonyms:
(S)-2-(4-iodophenyl)-N-(2-oxotetrahydrofuran-3-yl)acetamide | CHEMBL468790
Type:
Small organic molecule
Emp. Form.:
C12H12INO3
Mol. Mass.:
345.1331
SMILES:
Ic1ccc(CC(=O)N[C@H]2CCOC2=O)cc1 |r|
Structure:
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