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Target
Amine oxidase [flavin-containing] B
Ligand
BDBM50359577
Substrate
n/a
Meas. Tech.
ChEMBL_792695 (CHEMBL1930522)
IC50
2620±n/a nM
Citation
 Booysen, HP; Moraal, C; Terre'Blanche, G; Petzer, A; Bergh, JJ; Petzer, JP Thio- and aminocaffeine analogues as inhibitors of human monoamine oxidase. Bioorg Med Chem 19:7507-18 (2011) [PubMed]  Article 
Target
Name:
Amine oxidase [flavin-containing] B
Synonyms:
AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB)
Type:
Protein
Mol. Mass.:
58768.76
Organism:
Homo sapiens (Human)
Description:
P27338
Residue:
520
Sequence:
MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
  
Inhibitor
Name:
BDBM50359577
Synonyms:
CHEMBL1927672
Type:
Small organic molecule
Emp. Form.:
C13H20N4O2S
Mol. Mass.:
296.388
SMILES:
CC(C)CCSc1nc2n(C)c(=O)n(C)c(=O)c2n1C
Structure:
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