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Target
Midkine
Ligand
BDBM50364351
Substrate
n/a
Meas. Tech.
ChEMBL_805023 (CHEMBL1952884)
Kd
17.8±n/a nM
Citation
 Tamura, J; Tsutsumishita-Nakai, N; Nakao, Y; Kawano, M; Kato, S; Takeda, N; Nadanaka, S; Kitagawa, H Synthesis and interaction with midkine of biotinylated chondroitin sulfate tetrasaccharides. Bioorg Med Chem Lett 22:1371-4 (2012) [PubMed]  Article 
Target
Name:
Midkine
Synonyms:
ARAP | Amphiregulin-associated protein | MDK | MK | MK1 | MK_HUMAN | Midgestation and kidney protein | NEGF2 | Neurite outgrowth-promoting factor 2 | Neurite outgrowth-promoting protein
Type:
PROTEIN
Mol. Mass.:
15605.71
Organism:
Homo sapiens (Human)
Description:
ChEMBL_805023
Residue:
143
Sequence:
MQHRGFLLLTLLALLALTSAVAKKKDKVKKGGPGSECAEWAWGPCTPSSKDCGVGFREGTCGAQTQRIRCRVPCNWKKEFGADCKYKFENWGACDGGTGTKVRQGTLKKARYNAQCQETIRVTKPCTPKTKAKAKAKKGKGKD
  
Inhibitor
Name:
BDBM50364351
Synonyms:
CHEMBL1950107
Type:
Small organic molecule
Emp. Form.:
C51H82N6O36S3
Mol. Mass.:
1451.411
SMILES:
CC(=O)N[C@@H]1[C@@H](O)[C@@H](OS([O-])(=O)=O)[C@@H](CO)O[C@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@@H]2[C@@H](NC(C)=O)[C@H](O[C@H]3[C@H](O)[C@@H](O)[C@H](OCCNC(=O)CCOCCOCCOCCOCCNC(=O)CCCC[C@@H]4SC[C@@H]5NC(=O)N[C@H]45)O[C@@H]3C(O)=O)O[C@H](CO)[C@@H]2OS([O-])(=O)=O)O[C@@H]1C(O)=O |r|
Structure:
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