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Target
Neuromedin-B receptor
Ligand
BDBM50289794
Substrate
n/a
Meas. Tech.
ChEBML_88176
Ki
37±n/a nM
Citation
 Horwell, D; Kneen, C; Pritchard, M; Ratcliffe, G; Roberts, E; Suman-Chauhan, N; Steiner, K; Betche, H Design and synthesis of a targeted set of aromatic amino acid derivatives for identification of new lead compounds Bioorg Med Chem Lett 7:1957-1962 (1997)    Article 
Target
Name:
Neuromedin-B receptor
Synonyms:
Bombesin 1 | NMB-R | NMBR | NMBR_HUMAN | Neuromedin B | Neuromedin B receptor | Neuromedin-B receptor | Neuromedin-B-preferring bombesin receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
43447.11
Organism:
Homo sapiens (Human)
Description:
Bombesin 1 NMBR 0::P28336
Residue:
390
Sequence:
MPSKSLSNLSVTTGANESGSVPEGWERDFLPASDGTTTELVIRCVIPSLYLLIITVGLLGNIMLVKIFITNSAMRSVPNIFISNLAAGDLLLLLTCVPVDASRYFFDEWMFGKVGCKLIPVIQLTSVGVSVFTLTALSADRYRAIVNPMDMQTSGALLRTCVKAMGIWVVSVLLAVPEAVFSEVARISSLDNSSFTACIPYPQTDELHPKIHSVLIFLVYFLIPLAIISIYYYHIAKTLIKSAHNLPGEYNEHTKKQMETRKRLAKIVLVFVGCFIFCWFPNHILYMYRSFNYNEIDPSLGHMIVTLVARVLSFGNSCVNPFALYLLSESFRRHFNSQLCCGRKSYQERGTSYLLSSSAVRMTSLKSNAKNMVTNSVLLNGHSMKQEMAL
  
Inhibitor
Name:
BDBM50289794
Synonyms:
CHEMBL292119 | [2-(1H-Indol-3-yl)-1-isobutylcarbamoyl-ethyl]-carbamic acid 1-trityl-1H-imidazol-4-ylmethyl ester
Type:
Small organic molecule
Emp. Form.:
C39H39N5O3
Mol. Mass.:
625.7587
SMILES:
CC(C)CNC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)OCc1cn(cn1)C(c1ccccc1)(c1ccccc1)c1ccccc1
Structure:
Search PDB for entries with ligand similarity: