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Target
Matrix metalloproteinase-9
Ligand
BDBM50078571
Substrate
n/a
Meas. Tech.
ChEBML_102118
IC50
0.500000±n/a nM
Citation
 Hanessian, S; Bouzbouz, S; Boudon, A; Tucker, GC; Peyroulan, D Picking the S1, S1' and S2' pockets of matrix metalloproteinases. A niche for potent acyclic sulfonamide inhibitors. Bioorg Med Chem Lett 9:1691-6 (1999) [PubMed]  Article 
Target
Name:
Matrix metalloproteinase-9
Synonyms:
92 kDa gelatinase | 92 kDa type IV collagenase | Clg4b | GELB | Gelatinase B | MMP-9 | MMP9_MOUSE | Matrix metalloproteinase 9 | Matrix metalloproteinase-9 | Mmp9
Type:
PROTEIN
Mol. Mass.:
80529.41
Organism:
Mus musculus
Description:
ChEMBL_71659
Residue:
730
Sequence:
MSPWQPLLLALLAFGCSSAAPYQRQPTFVVFPKDLKTSNLTDTQLAEAYLYRYGYTRAAQMMGEKQSLRPALLMLQKQLSLPQTGELDSQTLKAIRTPRCGVPDVGRFQTFKGLKWDHHNITYWIQNYSEDLPRDMIDDAFARAFAVWGEVAPLTFTRVYGPEADIVIQFGVAEHGDGYPFDGKDGLLAHAFPPGAGVQGDAHFDDDELWSLGKGVVIPTYYGNSNGAPCHFPFTFEGRSYSACTTDGRNDGTPWCSTTADYDKDGKFGFCPSERLYTEHGNGEGKPCVFPFIFEGRSYSACTTKGRSDGYRWCATTANYDQDKLYGFCPTRVDATVVGGNSAGELCVFPFVFLGKQYSSCTSDGRRDGRLWCATTSNFDTDKKWGFCPDQGYSLFLVAAHEFGHALGLDHSSVPEALMYPLYSYLEGFPLNKDDIDGIQYLYGRGSKPDPRPPATTTTEPQPTAPPTMCPTIPPTAYPTVGPTVGPTGAPSPGPTSSPSPGPTGAPSPGPTAPPTAGSSEASTESLSPADNPCNVDVFDAIAEIQGALHFFKDGWYWKFLNHRGSPLQGPFLTARTWPALPATLDSAFEDPQTKRVFFFSGRQMWVYTGKTVLGPRSLDKLGLGPEVTHVSGLLPRRLGKALLFSKGRVWRFDLKSQKVDPQSVIRVDKEFSGVPWNSHDIFQYQDKAYFCHGKFFWRVSFQNEVNKVDHEVNQVDDVGYVTYDLLQCP
  
Inhibitor
Name:
BDBM50078571
Synonyms:
(R)-2-[[(Benzhydryl-carbamoyl)-methyl]-(4-methoxy-benzenesulfonyl)-amino]-4-benzylsulfanyl-N-hydroxy-butyramide | CHEMBL47468
Type:
Small organic molecule
Emp. Form.:
C33H35N3O6S2
Mol. Mass.:
633.778
SMILES:
COc1ccc(cc1)S(=O)(=O)N(CC(=O)NC(c1ccccc1)c1ccccc1)[C@H](CCSCc1ccccc1)C(=O)NO
Structure:
Search PDB for entries with ligand similarity: