Reaction Details Report a problem with these data
Target
Melanocortin receptor 4
Ligand
BDBM50129192
Substrate
n/a
Meas. Tech.
ChEBML_106494
EC50
>100000±n/a nM
Citation
 Joseph, CG; Bauzo, RM; Xiang, Z; Haskell-Luevano, C Urea small molecule agonists on mouse melanocortin receptors. Bioorg Med Chem Lett 13:2079-82 (2003) [PubMed]  Article 
Target
Name:
Melanocortin receptor 4
Synonyms:
MC4-R | MC4R_MOUSE | Mc4r
Type:
PROTEIN
Mol. Mass.:
36964.43
Organism:
Mus musculus
Description:
ChEMBL_1498850
Residue:
332
Sequence:
MNSTHHHGMYTSLHLWNRSSYGLHGNASESLGKGHPDGGCYEQLFVSPEVFVTLGVISLLENILVIVAIAKNKNLHSPMYFFICSLAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAVDRYFTIFYALQYHNIMTVRRVGIIISCIWAACTVSGVLFIIYSDSSAVIICLISMFFTMLVLMASLYVHMFLMARLHIKRIAVLPGTGTIRQGTNMKGAITLTILIGVFVVCWAPFFLHLLFYISCPQNPYCVCFMSHFNLYLILIMCNAVIDPLIYALRSQELRKTFKEIICFYPLGGICELSSRY
  
Inhibitor
Name:
BDBM50129192
Synonyms:
CHEMBL431523 | N-(4-Amino-butyl)-3-(1H-indol-3-yl)-2-(3-phenethyl-ureido)-propionamide
Type:
Small organic molecule
Emp. Form.:
C24H31N5O2
Mol. Mass.:
421.5352
SMILES:
NCCCCNC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)NCCc1ccccc1
Structure:
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