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Target
Mu-type opioid receptor
Ligand
BDBM50125255
Substrate
n/a
Meas. Tech.
ChEMBL_147666 (CHEMBL756580)
Ki
1000±n/a nM
Citation
 Kiddle, JJ; McCreery, HJ; Soles, S Synthesis and binding affinity of neuropeptide Y at opiate receptors. Bioorg Med Chem Lett 13:1029-31 (2003) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
44789.51
Organism:
Homo sapiens (Human)
Description:
P35372
Residue:
400
Sequence:
MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCPPTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNIEQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50125255
Synonyms:
(R)-2-[((S)-1-{(R)-6-Amino-2-[(S)-2-({(S)-1-[(S)-2-amino-3-(4-hydroxy-phenyl)-propionyl]-pyrrolidine-2-carbonyl}-amino)-3-hydroxy-propionyl]-hexanoyl}-pyrrolidine-2-carbonyl)-amino]-succinic acid | CHEMBL276502
Type:
Small organic molecule
Emp. Form.:
C32H46N6O11
Mol. Mass.:
690.7412
SMILES:
NCCCC[C@H](C(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@H](CC(O)=O)C(O)=O
Structure:
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