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Target
Carbonic anhydrase 13
Ligand
BDBM10872
Substrate
n/a
Meas. Tech.
ChEBML_45453
Ki
1.3±n/a nM
Citation
 Lehtonen, JM; Parkkila, S; Vullo, D; Casini, A; Scozzafava, A; Supuran, CT Carbonic anhydrase inhibitors. Inhibition of cytosolic isozyme XIII with aromatic and heterocyclic sulfonamides: a novel target for the drug design. Bioorg Med Chem Lett 14:3757-62 (2004) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 13
Synonyms:
CA-XIII | CAH13_MOUSE | Ca13 | Car13 | Carbonate dehydratase XIII | Carbonic anhydrase 13 | Carbonic anhydrase XIII
Type:
Enzyme
Mol. Mass.:
29522.80
Organism:
Mus musculus (mouse)
Description:
Murine cloned isozyme
Residue:
262
Sequence:
MARLSWGYGEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKIISNSGHSFNVDFDDTEDKSVLRGGPLTGNYRLRQFHLHWGSADDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNFDPLCLLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAAFLLSNHRPPQPLKGRRVRASFY
  
Inhibitor
Name:
BDBM10872
Synonyms:
4-amino-N-[2-(4-sulfamoylphenyl)ethyl]benzene-1-sulfonamide | CHEMBL7146 | aromatic/heteroaromatic sulfonamide 17
Type:
Small organic molecule
Emp. Form.:
C14H17N3O4S2
Mol. Mass.:
355.432
SMILES:
Nc1ccc(cc1)S(=O)(=O)NCCc1ccc(cc1)S(N)(=O)=O
Structure:
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