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Target
D(2) dopamine receptor
Ligand
BDBM50018643
Substrate
n/a
Meas. Tech.
ChEBML_61412
IC50
25.0±n/a nM
Citation
 Wikström, H; Andersson, B; Elebring, T; Svensson, K; Carlsson, A; Largent, B N-substituted 1,2,3,4,4a,5,6,10b-octahydrobenzo[f]quinolines and 3-phenylpiperidines: effects on central dopamine and sigma receptors. J Med Chem 30:2169-74 (1988) [PubMed]  Article 
Target
Name:
D(2) dopamine receptor
Synonyms:
DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
50931.60
Organism:
Rattus norvegicus (rat)
Description:
P61169
Residue:
444
Sequence:
MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVSREKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTASILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQNECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPLKGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPPSHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMSRRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNSAVNPIIYTTFNIEFRKAFMKILHC
  
Inhibitor
Name:
BDBM50018643
Synonyms:
(R,R)-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol | (S,S)-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol | 4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol | CHEMBL67583 | rac-4-Propyl-1,2,3,4,4a,5,6,10b-octahydro-benzo[f]quinolin-9-ol
Type:
Small organic molecule
Emp. Form.:
C16H23NO
Mol. Mass.:
245.3599
SMILES:
CCCN1CCCC2C1CCc1ccc(O)cc21
Structure:
Search PDB for entries with ligand similarity: