Reaction Details Report a problem with these data
Target
Cytosol aminopeptidase
Ligand
BDBM50017377
Substrate
n/a
Meas. Tech.
ChEBML_98405
Ki
240000±n/a nM
Citation
 Giannousis, PP; Bartlett, PA Phosphorus amino acid analogues as inhibitors of leucine aminopeptidase. J Med Chem 30:1603-9 (1987) [PubMed]  Article 
Target
Name:
Cytosol aminopeptidase
Synonyms:
AMPL_HUMAN | Aminopeptidase | LAP3 | LAPEP | Leucine aminopeptidase | PEPS
Type:
PROTEIN
Mol. Mass.:
56171.75
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1507539
Residue:
519
Sequence:
MFLLPLPAAGRVVVRRLAVRRFGSRSLSTADMTKGLVLGIYSKEKEDDVPQFTSAGENFDKLLAGKLRETLNISGPPLKAGKTRTFYGLHQDFPSVVLVGLGKKAAGIDEQENWHEGKENIRAAVAAGCRQIQDLELSSVEVDPCGDAQAAAEGAVLGLYEYDDLKQKKKMAVSAKLYGSGDQEAWQKGVLFASGQNLARQLMETPANEMTPTRFAEIIEKNLKSASSKTEVHIRPKSWIEEQAMGSFLSVAKGSDEPPVFLEIHYKGSPNANEPPLVFVGKGITFDSGGISIKASANMDLMRADMGGAATICSAIVSAAKLNLPINIIGLAPLCENMPSGKANKPGDVVRAKNGKTIQVDNTDAEGRLILADALCYAHTFNPKVILNAATLTGAMDVALGSGATGVFTNSSWLWNKLFEASIETGDRVWRMPLFEHYTRQVVDCQLADVNNIGKYRSAGACTAAAFLKEFVTHPKWAHLDIAGVMTNKDEVPYLRKGMTGRPTRTLIEFLLRFSQDNA
  
Inhibitor
Name:
BDBM50017377
Synonyms:
(1-Amino-ethyl)-phosphonic acid | 1-Ammonium-ethanephosphonic acid anion | 1-aminoethylphosphonic acid | CHEMBL296494 | [(1R)-1-AMINOETHYL]PHOSPHONIC ACID
Type:
Small organic molecule
Emp. Form.:
C2H8NO3P
Mol. Mass.:
125.0636
SMILES:
CC(N)P(O)(O)=O
Structure:
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