Reaction Details Report a problem with these data
Target
Indolethylamine N-methyltransferase
Ligand
BDBM50367839
Substrate
n/a
Meas. Tech.
ChEBML_89038
Ki
12000±n/a nM
Citation
 Broom, AD Rational design of enzyme inhibitors: multisubstrate analogue inhibitors. J Med Chem 32:2-7 (1989) [PubMed]  Article 
Target
Name:
Indolethylamine N-methyltransferase
Synonyms:
Amine N-methyltransferase | Aromatic alkylamine N-methyltransferase | Arylamine N-methyltransferase | INMT | INMT_HUMAN | Indolamine N-methyltransferase
Type:
PROTEIN
Mol. Mass.:
28884.19
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1333668
Residue:
263
Sequence:
MKGGFTGGDEYQKHFLPRDYLATYYSFDGSPSPEAEMLKFNLECLHKTFGPGGLQGDTLIDIGSGPTIYQVLAACDSFQDITLSDFTDRNREELEKWLKKEPGAYDWTPAVKFACELEGNSGRWEEKEEKLRAAVKRVLKCDVHLGNPLAPAVLPLADCVLTLLAMECACCSLDAYRAALCNLASLLKPGGHLVTTVTLRLPSYMVGKREFSCVALEKEEVEQAVLDAGFDIEQLLHSPQSYSVTNAANNGVCFIVARKKPGP
  
Inhibitor
Name:
BDBM50367839
Synonyms:
CHEMBL2368635
Type:
Small organic molecule
Emp. Form.:
C23H29IN6O3S
Mol. Mass.:
596.484
SMILES:
[I-].C[S+](CCCCc1c[nH]c2ccccc12)C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12 |r|
Structure:
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