Reaction Details Report a problem with these data
Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50009049
Substrate
n/a
Meas. Tech.
ChEBML_201295
Ki
3.9±n/a nM
Citation
 Glennon, RA; Smith, JD; Ismaiel, AM; el-Ashmawy, M; Battaglia, G; Fischer, JB Identification and exploitation of the sigma-opiate pharmacophore. J Med Chem 34:1094-8 (1991) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
Opioid receptor | Oprs1 | SGMR1_RAT | Sigma | Sigma non-opioid intracellular receptor 1 | Sigma opioid receptor | Sigma-1 | Sigmar1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
25266.54
Organism:
RAT
Description:
Q9R0C9
Residue:
223
Sequence:
MPWAVGRRWAWITLFLTIVAVLIQAVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSRLIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSHGHSGRYWAEISDTIISGTFHQWREGTTKSEVYYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLAFALSDTIFSTQDFLTLFYTLRAYARGLRLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50009049
Synonyms:
(+/-)(1-Methyl-2-phenyl-ethyl)-(4-phenyl-butyl)-amine; tosylate | (S)(1-Methyl-2-phenyl-ethyl)-(4-phenyl-butyl)-amine; tosylate | CHEMBL12047
Type:
Small organic molecule
Emp. Form.:
C19H25N
Mol. Mass.:
267.4085
SMILES:
CC(Cc1ccccc1)NCCCCc1ccccc1
Structure:
Search PDB for entries with ligand similarity: