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Target
Beta-2 adrenergic receptor
Ligand
BDBM50002147
Substrate
n/a
Meas. Tech.
ChEBML_37987
Ki
1390±n/a nM
Citation
 Meurer, LC; Tolman, RL; Chapin, EW; Saperstein, R; Vicario, PP; Zrada, MM; MacCoss, M Synthesis and hypoglycemic activity of substituted 8-(1-piperazinyl)imidazo[1,2-a]pyrazines. J Med Chem 35:3845-57 (1992) [PubMed]  Article 
Target
Name:
Beta-2 adrenergic receptor
Synonyms:
ADRB2_CAVPO | Adrb2 | adrenergic Beta2
Type:
Enzyme Catalytic Domain
Mol. Mass.:
46993.24
Organism:
GUINEA PIG
Description:
adrenergic Beta2 ADRB2 GUINEA PIG::Q8K4Z4
Residue:
418
Sequence:
MGHLGNGSDFLLAPNASHAPDHNVTRERDEAWVVGMAIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGASHILMNMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVVILMVWVVSGLTSFLPIQMHWYRATHKDAINCYAEETCCDFFTNQAYAIASSIVSFYLPLVVMVFVYSRVFQVAKKQLQKIDRSEGRFHTQNLSQVEQDGRSGHGLRRSSKFYLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIPKEVYILLNWVGYVNSAFNPLIYCRSPDFRIAFQELLCLRRSALKAYGNDCSSNSNGKTDYTGEPNVCHQGQEKERELLCEDPPGTEDLVSCPGTVPSDSIDSQGRNYSTNDSLL
  
Inhibitor
Name:
BDBM50002147
Synonyms:
8-Piperazin-1-yl-3-propyl-imidazo[1,2-a]pyrazine; 2M.hydrochloride | CHEMBL545293
Type:
Small organic molecule
Emp. Form.:
C13H19N5
Mol. Mass.:
245.3235
SMILES:
CCCc1cnc2c(nccn12)N1CCNCC1
Structure:
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