Target
Mu-type opioid receptor
Ligand
BDBM50061062
Substrate
n/a
Meas. Tech.
ChEMBL_148398 (CHEMBL757106)
Ki
2093±n/a nM
Citation
 Dondio, GRonzoni, SEggleston, DSArtico, MPetrillo, PPetrone, GVisentin, LFarina, CVecchietti, VClarke, GD Discovery of a novel class of substituted pyrrolooctahydroisoquinolines as potent and selective delta opioid agonists, based on an extension of the message-address concept. J Med Chem 40:3192-8 (1997) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mor | OPIATE Mu | OPRM_MOUSE | Opioid receptors; mu and delta | Oprm | Oprm1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44431.62
Organism:
MOUSE
Description:
OPIATE Mu OPRM1 MOUSE::P42866
Residue:
398
Sequence:
MDSSAGPGNISDCSDPLAPASCSPAPGSWLNLSHVDGNQSDPCGPNRTGLGGSHSLCPQTGSPSMVTAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGNILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKIVNVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFIFAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHIYVIIKALITIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSTIEQQNSARIRQNTREHPSTANTVDRTNHQLENLEAETAPLP
  
Inhibitor
Name:
BDBM50061062
Synonyms:
3-((4aS,11aR)-2-Ethyl-1,2,3,4,5,6,11,11a-octahydro-pyrido[4,3-b]carbazol-4a-yl)-phenol | CHEMBL107670
Type:
Small organic molecule
Emp. Form.:
C23H26N2O
Mol. Mass.:
346.4653
SMILES:
CCN1CC[C@@]2(Cc3[nH]c4ccccc4c3C[C@H]2C1)c1cccc(O)c1
Structure:
Search PDB for entries with ligand similarity: