Reaction Details Report a problem with these data
Target
Phosphoribosyl pyrophosphate synthase-associated protein 2
Ligand
BDBM50105931
Substrate
n/a
Meas. Tech.
ChEMBL_154298 (CHEMBL763637)
Ki
17000000±n/a nM
Citation
 Hakimelahi, GH; Ly, TW; Moosavi-Movahedi, AA; Jain, ML; Zakerinia, M; Davari, H; Mei, HC; Sambaiah, T; Moshfegh, AA; Hakimelahi, S Design, synthesis, and biological evaluation of novel nucleoside and nucleotide analogues as agents against DNA viruses and/or retroviruses. J Med Chem 44:3710-20 (2001) [PubMed]  Article 
Target
Name:
Phosphoribosyl pyrophosphate synthase-associated protein 2
Synonyms:
KPRB_HUMAN | PRPSAP2 | Phosphoribosyl pyrophosphate synthetase-associated protein 2
Type:
PROTEIN
Mol. Mass.:
40929.34
Organism:
Homo sapiens (Human)
Description:
ChEMBL_154298
Residue:
369
Sequence:
MFCVTPPELETKMNITKGGLVLFSANSNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVAAIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD
  
Inhibitor
Name:
BDBM50105931
Synonyms:
CHEMBL123655 | [2-(6-Amino-purin-7-yl)-ethoxymethyl]-phosphonic acid
Type:
Small organic molecule
Emp. Form.:
C8H12N5O4P
Mol. Mass.:
273.1857
SMILES:
Nc1ncnc2ncn(CCOCP(O)(O)=O)c12
Structure:
Search PDB for entries with ligand similarity: