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Target
Phosphoribosyl pyrophosphate synthase-associated protein 2
Ligand
BDBM50369958
Substrate
n/a
Meas. Tech.
ChEMBL_154298 (CHEMBL763637)
Ki
790000±n/a nM
Citation
 Hakimelahi, GH; Ly, TW; Moosavi-Movahedi, AA; Jain, ML; Zakerinia, M; Davari, H; Mei, HC; Sambaiah, T; Moshfegh, AA; Hakimelahi, S Design, synthesis, and biological evaluation of novel nucleoside and nucleotide analogues as agents against DNA viruses and/or retroviruses. J Med Chem 44:3710-20 (2001) [PubMed]  Article 
Target
Name:
Phosphoribosyl pyrophosphate synthase-associated protein 2
Synonyms:
KPRB_HUMAN | PRPSAP2 | Phosphoribosyl pyrophosphate synthetase-associated protein 2
Type:
PROTEIN
Mol. Mass.:
40929.34
Organism:
Homo sapiens (Human)
Description:
ChEMBL_154298
Residue:
369
Sequence:
MFCVTPPELETKMNITKGGLVLFSANSNSSCMELSKKIAERLGVEMGKVQVYQEPNRETRVQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMRKRGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVAAIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFVMATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD
  
Inhibitor
Name:
BDBM50369958
Synonyms:
CHEMBL1790862
Type:
Small organic molecule
Emp. Form.:
C18H24N10O10P2
Mol. Mass.:
602.3917
SMILES:
Nc1ncnc2n(cnc12)[C@@H]1O[C@H](COP(O)(O)=O)[C@@H](OP(O)(=O)COCCn2cnc3ncnc(N)c23)[C@H]1O
Structure:
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