Reaction Details Report a problem with these data
Target
Adenosine receptor A1
Ligand
BDBM50370197
Substrate
n/a
Meas. Tech.
ChEMBL_28983 (CHEMBL640785)
Ki
7700±n/a nM
Citation
 Cappellacci, L; Barboni, G; Palmieri, M; Pasqualini, M; Grifantini, M; Costa, B; Martini, C; Franchetti, P Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues. J Med Chem 45:1196-202 (2002) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50370197
Synonyms:
CHEMBL606060
Type:
Small organic molecule
Emp. Form.:
C11H15N5O4
Mol. Mass.:
281.2679
SMILES:
CC1(O[C@H](CO)[C@@H](O)[C@H]1O)n1cnc2c(N)ncnc12 |r,w:1.10|
Structure:
Search PDB for entries with ligand similarity: