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Target
Adenosine receptor A1
Ligand
BDBM50370194
Substrate
n/a
Meas. Tech.
ChEMBL_28983 (CHEMBL640785)
Ki
23±n/a nM
Citation
 Cappellacci, L; Barboni, G; Palmieri, M; Pasqualini, M; Grifantini, M; Costa, B; Martini, C; Franchetti, P Ribose-modified nucleosides as ligands for adenosine receptors: synthesis, conformational analysis, and biological evaluation of 1'-C-methyl adenosine analogues. J Med Chem 45:1196-202 (2002) [PubMed]  Article 
Target
Name:
Adenosine receptor A1
Synonyms:
AA1R_RAT | ADENOSINE A1 | ADENOSINE A1 high | ADENOSINE A1 low | Adenosine A1 receptor (A1) | Adenosine receptor | Adenosine receptors A1 | Adora1
Type:
Protein
Mol. Mass.:
36704.13
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
326
Sequence:
MPPYISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGALVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKTVVTQRRAAVAIAGCWILSLVVGLTPMFGWNNLSVVEQDWRANGSVGEPVIKCEFEKVISMEYMVYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALILFLFALSWLPLHILNCITLFCPTCQKPSILIYIAIFLTHGNSAMNPIVYAFRIHKFRVTFLKIWNDHFRCQPKPPIDEDLPEEKAED
  
Inhibitor
Name:
BDBM50370194
Synonyms:
CHEMBL603974
Type:
Small organic molecule
Emp. Form.:
C20H25N5O4
Mol. Mass.:
399.4436
SMILES:
C[C@H](Cc1ccccc1)Nc1ncnc2n(cnc12)C1(C)O[C@H](CO)[C@@H](O)[C@H]1O |r|
Structure:
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