Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 6
Ligand
BDBM50130286
Substrate
n/a
Meas. Tech.
ChEMBL_3664 (CHEMBL620800)
Ki
0.600000±n/a nM
Citation
 Glennon, RA Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). J Med Chem 46:2795-812 (2003) [PubMed]  Article 
Target
Name:
5-hydroxytryptamine receptor 6
Synonyms:
5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
46968.43
Organism:
Homo sapiens (Human)
Description:
P50406
Residue:
440
Sequence:
MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQCRLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPGLFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGPRPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNFFNIDPAEPELRPHPLGIPTN
  
Inhibitor
Name:
BDBM50130286
Synonyms:
5-Chloro-3-methyl-benzo[b]thiophene-2-sulfonic acid [4-methoxy-3-(4-methyl-piperazin-1-yl)-phenyl]-amide | CHEMBL29846 | SB-258510
Type:
Small organic molecule
Emp. Form.:
C21H24ClN3O3S2
Mol. Mass.:
466.017
SMILES:
COc1ccc(NS(=O)(=O)c2sc3ccc(Cl)cc3c2C)cc1N1CCN(C)CC1
Structure:
Search PDB for entries with ligand similarity: