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Target
Nuclear receptor subfamily 1 group I member 3
Ligand
BDBM50422491
Substrate
n/a
Meas. Tech.
ChEMBL_48051 (CHEMBL875886)
IC50
5012±n/a nM
Citation
 Jyrkkärinne, J; Mäkinen, J; Gynther, J; Savolainen, H; Poso, A; Honkakoski, P Molecular determinants of steroid inhibition for the mouse constitutive androstane receptor. J Med Chem 46:4687-95 (2003) [PubMed]  Article 
Target
Name:
Nuclear receptor subfamily 1 group I member 3
Synonyms:
Car | Constitutive androstane receptor | NR1I3_MOUSE | Nr1i3 | Nuclear receptor subfamily 1 group I member 3 | Orphan nuclear receptor MB67
Type:
PROTEIN
Mol. Mass.:
40922.30
Organism:
Mus musculus
Description:
ChEMBL_48051
Residue:
358
Sequence:
MTAMLTLETMASEEEYGPRNCVVCGDRATGYHFHALTCEGCKGFFRRTVSKTIGPICPFAGRCEVSKAQRRHCPACRLQKCLNVGMRKDMILSAEALALRRARQAQRRAEKASLQLNQQQKELVQILLGAHTRHVGPMFDQFVQFKPPAYLFMHHRPFQPRGPVLPLLTHFADINTFMVQQIIKFTKDLPLFRSLTMEDQISLLKGAAVEILHISLNTTFCLQTENFFCGPLCYKMEDAVHAGFQYEFLESILHFHKNLKGLHLQEPEYVLMAATALFSPDRPGVTQREEIDQLQEEMALILNNHIMEQQSRLQSRFLYAKLMGLLADLRSINNAYSYELQRLEELSAMTPLLGEICS
  
Inhibitor
Name:
BDBM50422491
Synonyms:
CHEMBL3137947
Type:
Small organic molecule
Emp. Form.:
C19H28O2
Mol. Mass.:
288.4244
SMILES:
[H][C@@]12CCC(=O)C1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])CC(=O)CCC12C
Structure:
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