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Target
Melanocyte-stimulating hormone receptor
Ligand
BDBM50167683
Substrate
n/a
Meas. Tech.
ChEMBL_302571 (CHEMBL839532)
Ki
>5000±n/a nM
Citation
 Tian, X; Field, T; Mazur, AW; Ebetino, FH; Wos, JA; Crossdoersen, D; Pinney, BB; Sheldon, RJ Design, synthesis, and evaluation of proline based melanocortin receptor ligands. Bioorg Med Chem Lett 15:2819-23 (2005) [PubMed]  Article 
Target
Name:
Melanocyte-stimulating hormone receptor
Synonyms:
MC1-R | MC1R | MSH-R | MSHR | MSHR_HUMAN | Melanocortin MC1 | Melanocortin receptor (M1 and M4) | Melanocortin receptor 1 (MC-1) | Melanocortin receptor 1 (MC1-R) | Melanocortin receptor 1 (MC1R)
Type:
Enzyme
Mol. Mass.:
34717.23
Organism:
Homo sapiens (Human)
Description:
Q01726
Residue:
317
Sequence:
MAVQGSQRRLLGSLNSTPTAIPQLGLAANQTGARCLEVSISDGLFLSLGLVSLVENALVVATIAKNRNLHSPMYCFICCLALSDLLVSGSNVLETAVILLLEAGALVARAAVLQQLDNVIDVITCSSMLSSLCFLGAIAVDRYISIFYALRYHSIVTLPRARRAVAAIWVASVVFSTLFIAYYDHVAVLLCLVVFFLAMLVLMAVLYVHMLARACQHAQGIARLHKRQRPVHQGFGLKGAVTLTILLGIFFLCWGPFFLHLTLIVLCPEHPTCGCIFKNFNLFLALIICNAIIDPLIYAFHSQELRRTLKEVLTCSW
  
Inhibitor
Name:
BDBM50167683
Synonyms:
(2S,4S)-4-Benzyl-1-[(S)-5-guanidino-2-(2-naphthalen-2-yl-acetylamino)-pentanoyl]-pyrrolidine-2-carboxylic acid benzylamide | CHEMBL439522
Type:
Small organic molecule
Emp. Form.:
C37H42N6O3
Mol. Mass.:
618.7678
SMILES:
NC(=N)NCCC[C@H](NC(=O)Cc1ccc2ccccc2c1)C(=O)N1C[C@@H](Cc2ccccc2)C[C@H]1C(=O)NCc1ccccc1
Structure:
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