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Target
Delta-type opioid receptor
Ligand
BDBM50210415
Substrate
n/a
Meas. Tech.
ChEMBL_438624 (CHEMBL888955)
Ki
1783±n/a nM
Citation
 Ho, GD; Bercovici, A; Tulshian, D; Greenlee, WJ; Fawzi, A; Smith Torhan, A; Zhang, H Synthesis and structure-activity relationships of 4-hydroxy-4-phenylpiperidines as nociceptin receptor ligands: Part 1. Bioorg Med Chem Lett 17:3023-7 (2007) [PubMed]  Article 
Target
Name:
Delta-type opioid receptor
Synonyms:
D-OR-1 | DOR-1 | Delta opioid receptor | Delta-type opioid receptor (Delta) | OPIATE Delta | OPRD | OPRD1 | OPRD_HUMAN | OPRK1 | opioid receptor, delta 1
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
40382.98
Organism:
Homo sapiens (Human)
Description:
Competition binding assays were carried out using membrane preparations from transfected HN9.10 cells that constitutively expressed the delta opioid receptor.
Residue:
372
Sequence:
MEPAPSAGAELQPPLFANASDAYPSACPSAGANASGPPGARSASSLALAIAITALYSAVCAVGLLGNVLVMFGIVRYTKMKTATNIYIFNLALADALATSTLPFQSAKYLMETWPFGELLCKAVLSIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPAKAKLINICIWVLASGVGVPIMVMAVTRPRDGAVVCMLQFPSPSWYWDTVTKICVFLFAFVVPILIITVCYGLMLLRLRSVRLLSGSKEKDRSLRRITRMVLVVVGAFVVCWAPIHIFVIVWTLVDIDRRDPLVVAALHLCIALGYANSSLNPVLYAFLDENFKRCFRQLCRKPCGRPDPSSFSRAREATARERVTACTPSDGPGGGAAA
  
Inhibitor
Name:
BDBM50210415
Synonyms:
1-(bis(2-fluorophenyl)methyl)-4-phenylpiperidin-4-ol | CHEMBL228912
Type:
Small organic molecule
Emp. Form.:
C24H23F2NO
Mol. Mass.:
379.4423
SMILES:
OC1(CCN(CC1)C(c1ccccc1F)c1ccccc1F)c1ccccc1
Structure:
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