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Target
Kappa-type opioid receptor
Ligand
BDBM50210185
Substrate
n/a
Meas. Tech.
ChEMBL_443956 (CHEMBL893123)
Ki
585±n/a nM
Citation
 Weigl, M; Wünsch, B Synthesis of bridged piperazines with sigma receptor affinity. Eur J Med Chem 42:1247-62 (2007) [PubMed]  Article 
Target
Name:
Kappa-type opioid receptor
Synonyms:
Kappa Opioid Receptor | OPIATE Kappa | OPRK1 | OPRK_CAVPO | Opiate Kappa 1 | mu/kappa opioid receptor
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42744.99
Organism:
Cavia porcellus (domestic guinea pig)
Description:
P41144
Residue:
380
Sequence:
MGRRRQGPAQPASELPARNACLLPNGSAWLPGWAEPDGNGSAGPQDEQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIILGGTKVREDVDIIECSLQFPDDDYSWWDLFMKICVFVFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFIICWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPIKMRMERQSTSRVRNTVQDPAYMRNVDGVNKPV
  
Inhibitor
Name:
BDBM50210185
Synonyms:
(1R,2R,5S )-6-benzyl-2-benzyloxy-8-methyl-6,8-diazabicyclo[3.2.2]nonane | CHEMBL394352
Type:
Small organic molecule
Emp. Form.:
C22H28N2O
Mol. Mass.:
336.4705
SMILES:
CN1CC2CC[C@@H](OCc3ccccc3)C1CN2Cc1ccccc1 |w:15.17,3.3,TLB:7:6:17.16:2.1,0:1:17.16:4.5.6,THB:18:17:4.5.6:2.1|
Structure:
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