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Target
Tumor susceptibility gene 101 protein
Ligand
BDBM50371256
Substrate
n/a
Meas. Tech.
ChEMBL_461905 (CHEMBL944752)
IC50
13000±n/a nM
Citation
 Liu, F; Stephen, AG; Fisher, RJ; Burke, TR Protected aminooxyprolines for expedited library synthesis: application to Tsg101-directed proline-oxime containing peptides. Bioorg Med Chem Lett 18:1096-101 (2008) [PubMed]  Article 
Target
Name:
Tumor susceptibility gene 101 protein
Synonyms:
TS101_HUMAN | TSG101
Type:
PROTEIN
Mol. Mass.:
43943.30
Organism:
Homo sapiens (Human)
Description:
ChEMBL_800321
Residue:
390
Sequence:
MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIPVPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPPNPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRWRMKEEMDRAQAELNALKRTEEDLKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSSALEKMENQSENNDIDEVIIPTAPLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFLKHVRLLSRKQFQLRALMQKARKTAGLSDLY
  
Inhibitor
Name:
BDBM50371256
Synonyms:
CHEMBL1162967
Type:
Small organic molecule
Emp. Form.:
C77H93N13O25S
Mol. Mass.:
1632.699
SMILES:
COc1ccc(\C=N/OC2CCN(C2C(=O)NC(CCC(O)=O)C(=O)NC(CCC(O)=O)C(N)=O)C(=O)C2CCCCN2C(=O)C(C)NC(=O)C(NC(=O)C2CCCN2C(=O)C(CCC(O)=O)NC(=O)C2CCCN2C(=O)CCCCNC(=S)Nc2ccc3C(=O)OC4(c3c2)c2ccc(O)cc2Oc2cc(O)ccc42)C(C)O)cc1O
Structure:
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