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Target
Beta-lactamase
Ligand
BDBM50021959
Substrate
n/a
Meas. Tech.
ChEMBL_474299 (CHEMBL936078)
IC50
70±n/a nM
Citation
 Papagiannitsis, CC; Loli, A; Tzouvelekis, LS; Tzelepi, E; Arlet, G; Miriagou, V SCO-1, a novel plasmid-mediated class A beta-lactamase with carbenicillinase characteristics from Escherichia coli. Antimicrob Agents Chemother 51:2185-8 (2007) [PubMed]  Article 
Target
Name:
Beta-lactamase
Synonyms:
Beta-lactamase SCO-1 | SCO-1 carbenicillinase
Type:
PROTEIN
Mol. Mass.:
30647.09
Organism:
Escherichia coli
Description:
ChEMBL_474299
Residue:
288
Sequence:
MTRSALLIPLTTAAIALNAISPVYASDTHSIDDTVKQVETTLGAKVGIAVLDTGSQRAWFHRADDRFPMASTSKALTCAALLDKGQSFMNKEALIKKADLDEYAPVTSGIVGKKVSAADLCSITMRTSDNTAVNKVLEILGGPQAVTAYLRKTGDNITRLDRNEPDLNEGTPGDVRDTTTPRAILETLNKLVLGPTLGSDERKQLTTWLESNEVGDPLLRAGVPSDWRVADRTGAGGNGTRGVIAVMWPPKHAPIIAAIYITQTKATMEERNAAIASIGKAIAAEVLE
  
Inhibitor
Name:
BDBM50021959
Synonyms:
CHEMBL777 | MM 14151 | US9120808, Clavulanic acid potassium salt | antibiotic MM 14151 | clavulanic acid
Type:
Small organic molecule
Emp. Form.:
C8H9NO5
Mol. Mass.:
199.1608
SMILES:
OC\C=C1/O[C@@H]2CC(=O)N2[C@H]1C(O)=O |r|
Structure:
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