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Target
Prostaglandin E2 receptor EP1 subtype
Ligand
BDBM50376299
Substrate
n/a
Meas. Tech.
ChEMBL_475971 (CHEMBL931425)
Ki
142±n/a nM
Citation
 Beaulieu, C; Guay, D; Wang, Z; Leblanc, Y; Roy, P; Dufresne, C; Zamboni, R; Berthelette, C; Day, S; Tsou, N; Denis, D; Greig, G; Mathieu, MC; O'Neill, G Identification of prostaglandin D2 receptor antagonists based on a tetrahydropyridoindole scaffold. Bioorg Med Chem Lett 18:2696-700 (2008) [PubMed]  Article 
Target
Name:
Prostaglandin E2 receptor EP1 subtype
Synonyms:
PE2R1_HUMAN | PGE receptor, EP1 subtype | PTGER1 | Prostaglandin E2 receptor | Prostaglandin E2 receptor EP1 subtype | Prostaglandin E2 receptor EP1 subtype (EP1) | Prostanoid EP1 receptor
Type:
Enzyme
Mol. Mass.:
41834.57
Organism:
Homo sapiens (Human)
Description:
P34995
Residue:
402
Sequence:
MSPCGPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQAAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTAGRAPAGGACHFLGGCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLARVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARWRRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVEMVGQLVGIMVVSCICWSPMLVLVALAVGGWSSTSLQRPLFLAVRLASWNQILDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLRSSRHSGLSHF
  
Inhibitor
Name:
BDBM50376299
Synonyms:
CHEMBL412070
Type:
Small organic molecule
Emp. Form.:
C22H19ClFNO5S
Mol. Mass.:
463.906
SMILES:
CS(=O)(=O)c1cc(F)cc2n3CCC[C@H](CC(O)=O)c3c(C(=O)c3ccc(Cl)cc3)c12
Structure:
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