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Target
Tissue factor
Ligand
BDBM50079401
Substrate
n/a
Meas. Tech.
ChEMBL_508123 (CHEMBL1004860)
IC50
1000000±n/a nM
Citation
 Wang, J; Mahmud, SA; Bitterman, PB; Huo, Y; Slungaard, A Histone deacetylase inhibitors suppress TF-kappaB-dependent agonist-driven tissue factor expression in endothelial cells and monocytes. J Biol Chem 282:28408-18 (2007) [PubMed]  Article 
Target
Name:
Tissue factor
Synonyms:
CD_antigen=CD142 | Coagulation factor III | Coagulation factor VII/tissue factor | F3 | TF | TF_HUMAN | Thromboplastin | Tissue factor
Type:
PROTEIN
Mol. Mass.:
33067.61
Organism:
Homo sapiens (Human)
Description:
ChEMBL_936735
Residue:
295
Sequence:
METPAWPRVPRPETAVARTLLLGWVFAQVAGASGTTNTVAAYNLTWKSTNFKTILEWEPKPVNQVYTVQISTKSGDWKSKCFYTTDTECDLTDEIVKDVKQTYLARVFSYPAGNVESTGSAGEPLYENSPEFTPYLETNLGQPTIQSFEQVGTKVNVTVEDERTLVRRNNTFLSLRDVFGKDLIYTLYYWKSSSSGKKTAKTNTNEFLIDVDKGENYCFSVQAVIPSRTVNRKSTDSPVECMGQEKGEFREIFYIIGAVVFVVIILVIILAISLHKCRKAGVGQSWKENSPLNVS
  
Inhibitor
Name:
BDBM50079401
Synonyms:
CHEMBL62381 | Sodium butyrate | Sodium; butyrate | butanoate | butyrate
Type:
Small organic molecule
Emp. Form.:
C4H7O2
Mol. Mass.:
87.0977
SMILES:
CCCC([O-])=O
Structure:
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