Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM50272275
Substrate
n/a
Meas. Tech.
ChEMBL_510484 (CHEMBL1006425)
EC50
11±n/a nM
Citation
 Cheng, Y; Albrecht, BK; Brown, J; Buchanan, JL; Buckner, WH; DiMauro, EF; Emkey, R; Fremeau, RT; Harmange, JC; Hoffman, BJ; Huang, L; Huang, M; Lee, JH; Lin, FF; Martin, MW; Nguyen, HQ; Patel, VF; Tomlinson, SA; White, RD; Xia, X; Hitchcock, SA Discovery and optimization of a novel series of N-arylamide oxadiazoles as potent, highly selective and orally bioavailable cannabinoid receptor 2 (CB2) agonists. J Med Chem 51:5019-34 (2008) [PubMed]  Article 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2
Type:
Enzyme
Mol. Mass.:
39366.68
Organism:
Rattus norvegicus (Rat)
Description:
Q9QZN9
Residue:
360
Sequence:
MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILSSQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLDVRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYALRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
  
Inhibitor
Name:
BDBM50272275
Synonyms:
3-(3-(2-Chloro-4-fluorophenyl)-1,2,4-oxadiazol-5-yl)-N-(6-chloroquinolin-3-yl)propanamide | CHEMBL526345
Type:
Small organic molecule
Emp. Form.:
C20H13Cl2FN4O2
Mol. Mass.:
431.247
SMILES:
Fc1ccc(-c2noc(CCC(=O)Nc3cnc4ccc(Cl)cc4c3)n2)c(Cl)c1
Structure:
Search PDB for entries with ligand similarity: