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Target
Glycophorin-A
Ligand
BDBM50246052
Substrate
n/a
Meas. Tech.
ChEMBL_558160 (CHEMBL961629)
Kd
48000±n/a nM
Citation
 Ujihara, S; Oishi, T; Torikai, K; Konoki, K; Matsumori, N; Murata, M; Oshima, Y; Aimoto, S Interaction of ladder-shaped polyethers with transmembrane alpha-helix of glycophorin A as evidenced by saturation transfer difference NMR and surface plasmon resonance. Bioorg Med Chem Lett 18:6115-8 (2008) [PubMed]  Article 
Target
Name:
Glycophorin-A
Synonyms:
GLPA_HUMAN | GPA | GYPA
Type:
PROTEIN
Mol. Mass.:
16327.75
Organism:
Homo sapiens (Human)
Description:
ChEMBL_558160
Residue:
150
Sequence:
MYGKIIFVLLLSEIVSISASSTTGVAMHTSTSSSVTKSYISSQTNDTHKRDTYAATPRAHEVSEISVRTVYPPEEETGERVQLAHHFSEPEITLIIFGVMAGVIGTILLISYGIRRLIKKSPSDVKPLPSPDTDVPLSSVEIENPETSDQ
  
Inhibitor
Name:
BDBM50246052
Synonyms:
(1S,3R,5S,7R,9S,10R,12S,14R,17S,19R,21S,23R,25S,26R,28S,31R)-10-(benzyloxy)-9-[2-(benzyloxy)ethyl]-26-(hydroxymethyl)-14,31-dimethyl-4,8,13,18,22,27,32-heptaoxaheptacyclo[17.13.0.0^{3,17}.0^{5,14}.0^{7,12}.0^{21,31}.0^{23,28}]dotriacontan-25-ol | CHEMBL500181
Type:
Small organic molecule
Emp. Form.:
C44H60O11
Mol. Mass.:
764.9406
SMILES:
C[C@@]12CC[C@@H]3O[C@@H]4C[C@@H]5O[C@@H]6C[C@H](O)[C@@H](CO)O[C@H]6CC[C@@]5(C)O[C@H]4C[C@H]3O[C@H]1C[C@H]1O[C@@H](CCOCc3ccccc3)[C@@H](C[C@@H]1O2)OCc1ccccc1 |r|
Structure:
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