Reaction Details Report a problem with these data
Target
Adenosine receptor A3
Ligand
BDBM50013706
Substrate
n/a
Meas. Tech.
ChEMBL_566532 (CHEMBL955118)
Ki
>100000±n/a nM
Citation
 Lambertucci, C; Antonini, I; Buccioni, M; Dal Ben, D; Kachare, DD; Volpini, R; Klotz, KN; Cristalli, G 8-Bromo-9-alkyl adenine derivatives as tools for developing new adenosine A2A and A2B receptors ligands. Bioorg Med Chem 17:2812-22 (2009) [PubMed]  Article 
Target
Name:
Adenosine receptor A3
Synonyms:
A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
36197.32
Organism:
Homo sapiens (Human)
Description:
P0DMS8
Residue:
318
Sequence:
MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIAVGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKRVTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYFSFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFALSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKACVVCHPSDSLDTSIEKNSE
  
Inhibitor
Name:
BDBM50013706
Synonyms:
9-Benzyl-9H-adenine | 9-Benzyl-9H-purin-6-ylamine | 9-benzyl-9H-purin-6-amine | CHEMBL266094
Type:
Small organic molecule
Emp. Form.:
C12H11N5
Mol. Mass.:
225.2492
SMILES:
Nc1ncnc2n(Cc3ccccc3)cnc12
Structure:
Search PDB for entries with ligand similarity: