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Target
Histamine H3 receptor
Ligand
BDBM50247053
Substrate
n/a
Meas. Tech.
ChEMBL_563460 (CHEMBL961008)
Ki
0.16±n/a nM
Citation
 Lazewska, D; Kuder, K; Ligneau, X; Camelin, JC; Schunack, W; Stark, H; Kiec-Kononowicz, K Diether derivatives of homo- or substituted piperidines as non-imidazole histamine H3 receptor ligands. Bioorg Med Chem 17:3037-42 (2009) [PubMed]  Article 
Target
Name:
Histamine H3 receptor
Synonyms:
HISTAMINE H3 | HRH3 | HRH3_CAVPO | Histamine H3 receptor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
48753.61
Organism:
GUINEA PIG
Description:
HISTAMINE H3 HRH3 GUINEA PIG::Q9JI35
Residue:
445
Sequence:
MERAPPDGLMNASGALAGEAAAAAGGARTFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGVFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCTSSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMVLVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGAREAGPDPLPEAQSSPPQPPPGCWGCWPKGQGESMPLHRYGVGEAGPGAEAGEAALGGGSGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGHCVPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHSSLEHCWK
  
Inhibitor
Name:
BDBM50247053
Synonyms:
1-(3-(3-(4-chlorophenyl)propoxy)propyl)piperidine | CHEMBL462605 | Tiprolisant
Type:
Small organic molecule
Emp. Form.:
C17H26ClNO
Mol. Mass.:
295.847
SMILES:
Clc1ccc(CCCOCCCN2CCCCC2)cc1
Structure:
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