Reaction Details Report a problem with these data
Target
Carbonic anhydrase 13
Ligand
BDBM50022188
Substrate
n/a
Meas. Tech.
ChEMBL_595959 (CHEMBL1044461)
Ki
45±n/a nM
Citation
 Maresca, A; Temperini, C; Pochet, L; Masereel, B; Scozzafava, A; Supuran, CT Deciphering the mechanism of carbonic anhydrase inhibition with coumarins and thiocoumarins. J Med Chem 53:335-44 (2010) [PubMed]  Article 
Target
Name:
Carbonic anhydrase 13
Synonyms:
CA-XIII | CAH13_MOUSE | Ca13 | Car13 | Carbonate dehydratase XIII | Carbonic anhydrase 13 | Carbonic anhydrase XIII
Type:
Enzyme
Mol. Mass.:
29522.80
Organism:
Mus musculus (mouse)
Description:
Murine cloned isozyme
Residue:
262
Sequence:
MARLSWGYGEHNGPIHWNELFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPASAKIISNSGHSFNVDFDDTEDKSVLRGGPLTGNYRLRQFHLHWGSADDHGSEHVVDGVRYAAELHVVHWNSDKYPSFVEAAHESDGLAVLGVFLQIGEHNPQLQKITDILDSIKEKGKQTRFTNFDPLCLLPSSWDYWTYPGSLTVPPLLESVTWIVLKQPISISSQQLARFRSLLCTAEGESAAFLLSNHRPPQPLKGRRVRASFY
  
Inhibitor
Name:
BDBM50022188
Synonyms:
7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid | CHEMBL12567
Type:
Small organic molecule
Emp. Form.:
C11H8O5
Mol. Mass.:
220.1782
SMILES:
COc1ccc2c(cc(=O)oc2c1)C(O)=O
Structure:
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