Reaction Details Report a problem with these data
Target
Succinyl-diaminopimelate desuccinylase
Ligand
BDBM50311531
Substrate
n/a
Meas. Tech.
ChEMBL_617887 (CHEMBL1101552)
Ki
800000±n/a nM
Citation
 Gillner, D; Armoush, N; Holz, RC; Becker, DP Inhibitors of bacterial N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE) and demonstration of in vitro antimicrobial activity. Bioorg Med Chem Lett 19:6350-2 (2009) [PubMed]  Article 
Target
Name:
Succinyl-diaminopimelate desuccinylase
Synonyms:
DAPE_HAEIN | dapE
Type:
PROTEIN
Mol. Mass.:
41343.05
Organism:
Haemophilus influenzae
Description:
ChEMBL_617887
Residue:
377
Sequence:
MKEKVVSLAQDLIRRPSISPNDEGCQQIIAERLEKLGFQIEWMPFNDTLNLWAKHGTSEPVIAFAGHTDVVPTGDENQWSSPPFSAEIIDGMLYGRGAADMKGSLAAMIVAAEEYVKANPNHKGTIALLITSDEEATAKDGTIHVVETLMARDEKITYCMVGEPSSAKNLGDVVKNGRRGSITGNLYIQGIQGHVAYPHLAENPIHKAALFLQELTTYQWDKGNEFFPPTSLQIANIHAGTGSNNVIPAELYIQFNLRYCTEVTDEIIKQKVAEMLEKHNLKYRIEWNLSGKPFLTKPGKLLDSITSAIEETIGITPKAETGGGTSDGRFIALMGAEVVEFGPLNSTIHKVNECVSVEDLGKCGEIYHKMLVNLLDS
  
Inhibitor
Name:
BDBM50311531
Synonyms:
(2-Carboxyethyl)-phosphonic acid | 3-PHOSPHONOPROPANOIC ACID | CHEMBL1088324
Type:
Small organic molecule
Emp. Form.:
C3H7O5P
Mol. Mass.:
154.0584
SMILES:
OC(=O)CCP(O)(O)=O
Structure:
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