Target
Interleukin-5
Ligand
BDBM50242276
Substrate
n/a
Meas. Tech.
ChEMBL_638038 (CHEMBL1166941)
IC50
1400±n/a nM
Citation
 Thanigaimalai, PYang, HMSharma, VKKim, YJung, SH The scope of thallium nitrate oxidative cyclization of chalcones; synthesis and evaluation of isoflavone and aurone analogs for their inhibitory activity against interleukin-5. Bioorg Med Chem 18:4441-5 (2010) [PubMed]  Article 
Target
Name:
Interleukin-5
Synonyms:
IL5_MOUSE | Il-5 | Il5
Type:
PROTEIN
Mol. Mass.:
15414.97
Organism:
Mus musculus
Description:
ChEMBL_1464308
Residue:
133
Sequence:
MRRMLLHLSVLTLSCVWATAMEIPMSTVVKETLTQLSAHRALLTSNETMRLPVPTHKNHQLCIGEIFQGLDILKNQTVRGGTVEMLFQNLSLIKKYIDRQKEKCGEERRRTRQFLDYLQEFLGVMSTEWAMEG
  
Inhibitor
Name:
BDBM50242276
Synonyms:
CHEMBL486626 | Sophoricoside
Type:
Small organic molecule
Emp. Form.:
C21H20O10
Mol. Mass.:
432.3775
SMILES:
OC[C@H]1O[C@@H](Oc2ccc(cc2)-c2coc3cc(O)cc(O)c3c2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Structure:
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