Reaction Details Report a problem with these data
Target
Type-2 angiotensin II receptor
Ligand
BDBM50321078
Substrate
n/a
Meas. Tech.
ChEMBL_637186 (CHEMBL1167160)
Ki
3.6±n/a nM
Citation
 Mahalingam, AK; Wan, Y; Murugaiah, AM; Wallinder, C; Wu, X; Plouffe, B; Botros, M; Nyberg, F; Hallberg, A; Gallo-Payet, N; Alterman, M Selective angiotensin II AT(2) receptor agonists with reduced CYP 450 inhibition. Bioorg Med Chem 18:4570-90 (2010) [PubMed]  Article 
Target
Name:
Type-2 angiotensin II receptor
Synonyms:
Angiotensin type II receptor
Type:
PROTEIN
Mol. Mass.:
15474.49
Organism:
Sus scrofa
Description:
ChEMBL_1285617
Residue:
137
Sequence:
MAFPPEKYAQWSAGIALMKNILGFIIPLVFIATCYFGIRKHLLKTNSYGKNRITRDQVLNMAAAVVLAFIICWLPFHVLTFLDALAWMGIINSCEVIAVIDLALPFAILLGFTNSCINPFLYCFVGNRFQQKLRSVF
  
Inhibitor
Name:
BDBM50321078
Synonyms:
CHEMBL1164104 | N-Butyloxycarbonyl-3-[4-(3,4,4-trimethyl-2,5-dioxoimidazolidin-1-yl-methyl)-phenyl]-5-iso-butyl-thiophene-2-sulfonamide
Type:
Small organic molecule
Emp. Form.:
C26H35N3O6S2
Mol. Mass.:
549.703
SMILES:
CCCCOC(=O)NS(=O)(=O)c1sc(CC(C)C)cc1-c1ccc(CN2C(=O)N(C)C(C)(C)C2=O)cc1
Structure:
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