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Target
MO15-related protein kinase Pfmrk
Ligand
BDBM50066318
Substrate
n/a
Meas. Tech.
ChEMBL_640752 (CHEMBL1175693)
IC50
400±n/a nM
Citation
 Caridha, D; Kathcart, AK; Jirage, D; Waters, NC Activity of substituted thiophene sulfonamides against malarial and mammalian cyclin dependent protein kinases. Bioorg Med Chem Lett 20:3863-7 (2010) [PubMed]  Article 
Target
Name:
MO15-related protein kinase Pfmrk
Synonyms:
Protein kinase Pfmrk
Type:
PROTEIN
Mol. Mass.:
37992.30
Organism:
Plasmodium falciparum
Description:
ChEMBL_640752
Residue:
324
Sequence:
MENNSTERYIFKPNFLGEGSYGKVYKAYDTILKKEVAIKKMKLNEISNYIDDCGINFVLLREIKIMKEIKHKNIMSALDLYCEKDYINLVMEIMDYDLSKIINRKIFLTDSQKKCILLQILNGLNVLHKYYFMHRDLSPANIFINKKGEVKLADFGLCTKYGYDMYSDKLFRDKYKKNLNLTSKVVTLWYRAPELLLGSNKYNSSIDMWSFGCIFAELLLQKALFPGENEIDQLGKIFFLLGTPNENNWPEALCLPLYTEFTKATKKDFKTYFKIDDDDCIDLLTSFLKLNAHERISAEDAMKHRYFFNDPLPCDISQLPFNDL
  
Inhibitor
Name:
BDBM50066318
Synonyms:
CHEMBL108888 | N'-(2-fluorobenzoyl)-2-naphthohydrazide | Naphthalene-2-carboxylic acid N'-(2-fluoro-benzoyl)-hydrazide
Type:
Small organic molecule
Emp. Form.:
C18H13FN2O2
Mol. Mass.:
308.3064
SMILES:
Fc1ccccc1C(=O)NNC(=O)c1ccc2ccccc2c1
Structure:
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