Reaction Details Report a problem with these data
Target
Mu-type opioid receptor
Ligand
BDBM21123
Substrate
n/a
Meas. Tech.
ChEMBL_639794 (CHEMBL1175739)
IC50
47±n/a nM
Citation
 Lee, YS; Fernandes, S; Kulkarani, V; Mayorov, A; Davis, P; Ma, SW; Brown, K; Gillies, RJ; Lai, J; Porreca, F; Hruby, VJ Design and synthesis of trivalent ligands targeting opioid, cholecystokinin, and melanocortin receptors for the treatment of pain. Bioorg Med Chem Lett 20:4080-4 (2010) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM21123
Synonyms:
(2S)-2-{2-[(2R)-2-[(2S)-2-amino-3-(4-hydroxyphenyl)propanamido]propanamido]acetamido}-3-phenylpropanamide | Enkephalin Amide | YDAGF-NH2
Type:
Peptide
Emp. Form.:
C23H29N5O5
Mol. Mass.:
455.5069
SMILES:
C[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(N)=O
Structure:
Search PDB for entries with ligand similarity: