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Target
Mu-type opioid receptor
Ligand
BDBM50334992
Substrate
n/a
Meas. Tech.
ChEMBL_702699 (CHEMBL1657773)
IC50
4.7±n/a nM
Citation
 Cowell, SM; Hanlon, KE Development of potent µ and d opioid agonists with high lipophilicity. J Med Chem 54:382-6 (2011) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50334992
Synonyms:
(R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanamido)-N-((S)-1-oxo-3-phenyl-1-(4-(N-phenylpropionamido)piperidin-1-yl)propan-2-yl)hexanamide | CHEMBL1649939
Type:
Small organic molecule
Emp. Form.:
C40H53N5O5
Mol. Mass.:
683.8793
SMILES:
CCCC[C@@H](NC(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC(CC1)N(C(=O)CC)c1ccccc1 |r|
Structure:
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