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Target
Mu-type opioid receptor
Ligand
BDBM50334990
Substrate
n/a
Meas. Tech.
ChEMBL_702699 (CHEMBL1657773)
IC50
4.8±n/a nM
Citation
 Cowell, SM; Hanlon, KE Development of potent µ and d opioid agonists with high lipophilicity. J Med Chem 54:382-6 (2011) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50334990
Synonyms:
(R)-2-((S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoyl)-N-(2-((S)-3-(4-chlorophenyl)-1-oxo-1-(4-(N-phenylpropionamido)piperidin-1-yl)propan-2-ylamino)-2-oxoethyl)-1,2,3,4-tetrahydroisoquinoline-3-carboxamide | CHEMBL1649948
Type:
Small organic molecule
Emp. Form.:
C46H53ClN6O6
Mol. Mass.:
821.403
SMILES:
CCC(=O)N(C1CCN(CC1)C(=O)[C@H](Cc1ccc(Cl)cc1)NC(=O)CNC(=O)[C@H]1Cc2ccccc2CN1C(=O)[C@@H](N)Cc1c(C)cc(O)cc1C)c1ccccc1 |r|
Structure:
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