Reaction Details Report a problem with these data
Target
Pteridine reductase 1
Ligand
BDBM50335099
Substrate
n/a
Meas. Tech.
ChEMBL_702836 (CHEMBL1655366)
IC50
1000000±n/a nM
Citation
 Shi, K; Huang, Q; Huang, Y; Lee, TC; Yu, H Reducing the brittleness of zein films through chemical modification. J Agric Food Chem 59:56-61 (2011) [PubMed]  Article 
Target
Name:
Pteridine reductase 1
Synonyms:
HMTXR | PTR1 | PTR1_LEIMA
Type:
PROTEIN
Mol. Mass.:
30459.34
Organism:
Leishmania major
Description:
ChEMBL_1470027
Residue:
288
Sequence:
MTAPTVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQADLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRNDEDGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRFAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGLSVLVDDMPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAKYITGTCVKVDGGYSLTRA
  
Inhibitor
Name:
BDBM50335099
Synonyms:
4-chlorobenzo[d]thiazol-2-amine | CHEMBL1413383 | EN300-157593
Type:
Small organic molecule
Emp. Form.:
C7H5ClN2S
Mol. Mass.:
184.646
SMILES:
Nc1nc2c(Cl)cccc2s1
Structure:
Search PDB for entries with ligand similarity: