Reaction Details Report a problem with these data
Target
Transcriptional activator protein LuxR
Ligand
BDBM50350709
Substrate
n/a
Meas. Tech.
ChEMBL_762767 (CHEMBL1816069)
IC50
130±n/a nM
Citation
 McInnis, CE; Blackwell, HE Thiolactone modulators of quorum sensing revealed through library design and screening. Bioorg Med Chem 19:4820-8 (2011) [PubMed]  Article 
Target
Name:
Transcriptional activator protein LuxR
Synonyms:
LUXR_ALIFS | luxR
Type:
PROTEIN
Mol. Mass.:
28563.86
Organism:
Vibrio fischeri
Description:
ChEMBL_831639
Residue:
250
Sequence:
MKNINADDTYRIINKIKACRSNNDINQCLSDMTKMVHCEYYLLAIIYPHSMVKSDISILDNYPKKWRQYYDDANLIKYDPIVDYSNSNHSPINWNIFENNAVNKKSPNVIKEAKTSGLITGFSFPIHTANNGFGMLSFAHSEKDNYIDSLFLHACMNIPLIVPSLVDNYRKINIANNKSNNDLTKREKECLAWACEGKSSWDISKILGCSERTVTFHLTNAQMKLNTTNRCQSISKAILTGAIDCPYFKN
  
Inhibitor
Name:
BDBM50350709
Synonyms:
CHEMBL1812080
Type:
Small organic molecule
Emp. Form.:
C12H21NO2S
Mol. Mass.:
243.366
SMILES:
CCCCCCCC(=O)N[C@H]1CCSC1=O |r|
Structure:
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