Reaction Details Report a problem with these data
Target
Neuropeptide Y receptor type 5
Ligand
BDBM50379607
Substrate
n/a
Meas. Tech.
ChEMBL_811654 (CHEMBL2014167)
Ki
1±n/a nM
Citation
 Wu, L; Lu, K; Packiarajan, M; Jubian, V; Chandrasena, G; Wolinsky, TC; Walker, MW Indolyl and dihydroindolyl N-glycinamides as potent and in vivo active NPY5 antagonists. Bioorg Med Chem Lett 22:2167-71 (2012) [PubMed]  Article 
Target
Name:
Neuropeptide Y receptor type 5
Synonyms:
NPY-Y5 | NPY-Y5 receptor | NPY5-R | NPY5R | NPY5R_HUMAN | NPYR5 | NPYY5 | Neuropeptide Y receptor type 5 | Neuropeptide Y receptor type 5 ( NPY Y5) | Y5 receptor
Type:
Enzyme
Mol. Mass.:
50746.64
Organism:
Homo sapiens (Human)
Description:
Q15761
Residue:
445
Sequence:
MDLELDEYYNKTLATENNTAATRNSDFPVWDDYKSSVDDLQYFLIGLYTFVSLLGFMGNLLILMALMKKRNQKTTVNFLIGNLAFSDILVVLFCSPFTLTSVLLDQWMFGKVMCHIMPFLQCVSVLVSTLILISIAIVRYHMIKHPISNNLTANHGYFLIATVWTLGFAICSPLPVFHSLVELQETFGSALLSSRYLCVESWPSDSYRIAFTISLLLVQYILPLVCLTVSHTSVCRSISCGLSNKENRLEENEMINLTLHPSKKSGPQVKLSGSHKWSYSFIKKHRRRYSKKTACVLPAPERPSQENHSRILPENFGSVRSQLSSSSKFIPGVPTCFEIKPEENSDVHELRVKRSVTRIKKRSRSVFYRLTILILVFAVSWMPLHLFHVVTDFNDNLISNRHFKLVYCICHLLGMMSCCLNPILYGFLNNGIKADLVSLIHCLHM
  
Inhibitor
Name:
BDBM50379607
Synonyms:
CHEMBL2013021
Type:
Small organic molecule
Emp. Form.:
C20H28ClN3O3S
Mol. Mass.:
425.973
SMILES:
CC(C)S(=O)(=O)NC[C@H]1CC[C@@H](CC1)NC(=O)Cn1ccc2ccc(Cl)cc12 |r,wU:8.7,wD:11.14,(34.5,-46.23,;33.16,-45.46,;33.17,-43.92,;31.83,-46.22,;32.59,-47.55,;31.06,-47.54,;30.5,-45.45,;29.16,-46.22,;27.83,-45.45,;26.5,-46.21,;25.17,-45.45,;25.17,-43.91,;26.5,-43.13,;27.83,-43.91,;23.84,-43.14,;22.5,-43.92,;22.51,-45.46,;21.17,-43.15,;19.84,-43.93,;19.67,-45.45,;18.16,-45.78,;17.39,-44.45,;15.89,-44.13,;15.41,-42.68,;16.44,-41.52,;15.96,-40.06,;17.95,-41.84,;18.42,-43.3,)|
Structure:
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