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Target
Regulator of G-protein signaling 4
Ligand
BDBM50384754
Substrate
n/a
Meas. Tech.
ChEMBL_821035 (CHEMBL2039222)
IC50
13±n/a nM
Citation
 Turner, EM; Blazer, LL; Neubig, RR; Husbands, SM Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins. ACS Med Chem Lett 3:146-150 (2012) [PubMed]  Article 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM50384754
Synonyms:
CHEMBL2037234
Type:
Small organic molecule
Emp. Form.:
C17H15FN2O2S
Mol. Mass.:
330.377
SMILES:
Cc1ccc(Cn2sc(=O)n(Cc3ccc(F)cc3)c2=O)cc1
Structure:
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