Reaction Details Report a problem with these data
Target
Regulator of G-protein signaling 4
Ligand
BDBM7779
Substrate
n/a
Meas. Tech.
ChEMBL_821035 (CHEMBL2039222)
IC50
14±n/a nM
Citation
 Turner, EM; Blazer, LL; Neubig, RR; Husbands, SM Small Molecule Inhibitors of Regulator of G Protein Signalling (RGS) Proteins. ACS Med Chem Lett 3:146-150 (2012) [PubMed]  Article 
Target
Name:
Regulator of G-protein signaling 4
Synonyms:
RGP4 | RGS4 | RGS4_HUMAN | Regulator of G-protein signaling 4 (RGS4)
Type:
Enzyme
Mol. Mass.:
23263.51
Organism:
Homo sapiens (Human)
Description:
P49798
Residue:
205
Sequence:
MCKGLAGLPASCLRSAKDMKHRLGFLLQKSDSCEHNSSHNKKDKVVICQRVSQEEVKKWAESLENLISHECGLAAFKAFLKSEYSEENIDFWISCEEYKKIKSPSKLSPKAKKIYNEFISVQATKEVNLDSCTREETSRNMLEPTITCFDEAQKKIFNLMEKDSYRRFLKSRFYLDLVNPSSCGAEKQKGAKSSADCASLVPQCA
  
Inhibitor
Name:
BDBM7779
Synonyms:
4-butyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione | 4-n-Butyl-2-ethyl-1,2,4-thiadiazolidine-3,5-dione | Thiadiazolidinone (TDZD) deriv. 6
Type:
Small organic molecule
Emp. Form.:
C8H14N2O2S
Mol. Mass.:
202.274
SMILES:
CCCCn1c(=O)sn(CC)c1=O
Structure:
Search PDB for entries with ligand similarity: