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Target
Dual specificity protein kinase CLK1
Ligand
BDBM50385580
Substrate
n/a
Meas. Tech.
ChEMBL_824956 (CHEMBL2045475)
IC50
300±n/a nM
Citation
 Deslandes, S; Lamoral-Theys, D; Frongia, C; Chassaing, S; Bruyère, C; Lozach, O; Meijer, L; Ducommun, B; Kiss, R; Delfourne, E Synthesis and biological evaluation of analogs of the marine alkaloids granulatimide and isogranulatimide. Eur J Med Chem 54:626-36 (2012) [PubMed]  Article 
Target
Name:
Dual specificity protein kinase CLK1
Synonyms:
CDC-like kinase 1 | CLK1_MOUSE | Clk | Clk1 | Protein kinase STY | Sty
Type:
PROTEIN
Mol. Mass.:
57124.52
Organism:
Mus musculus
Description:
ChEMBL_1502245
Residue:
483
Sequence:
MRHSKRTYCPDWDERDWDYGTWRSSSSHKRKKRSHSSAREQKRCRYDHSKTTDSYYLESRSINEKAYHSRRYVDEYRNDYMGYEPGHPYGEPGSRYQMHSSKSSGRSGRSSYKSKHRSRHHTSQHHSHGKSHRRKRSRSVEDDEEGHLICQSGDVLSARYEIVDTLGEGAFGKVVECIDHKVGGRRVAVKIVKNVDRYCEAAQSEIQVLEHLNTTDPHSTFRCVQMLEWFEHRGHICIVFELLGLSTYDFIKENSFLPFRMDHIRKMAYQICKSVNFLHSNKLTHTDLKPENILFVKSDYTEAYNPKMKRDERTIVNPDIKVVDFGSATYDDEHHSTLVSTRHYRAPEVILALGWSQPCDVWSIGCILIEYYLGFTVFPTHDSREHLAMMERILGPLPKHMIQKTRKRRYFHHDRLDWDEHSSAGRYVSRRCKPLKEFMLSQDAEHELLFDLIGKMLEYDPAKRITLKEALKHPFFYPLKKHT
  
Inhibitor
Name:
BDBM50385580
Synonyms:
CHEMBL2041914
Type:
Small organic molecule
Emp. Form.:
C15H8N4O2
Mol. Mass.:
276.2496
SMILES:
O=C1NC(=O)c2c1c1ccnn1c1[nH]c3ccccc3c21
Structure:
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