Reaction Details Report a problem with these data
Target
Orphan methyltransferase M.SssI
Ligand
BDBM50389483
Substrate
n/a
Meas. Tech.
ChEMBL_832310 (CHEMBL2066848)
Ki
3400000±n/a nM
Citation
 Plitta, B; Adamska, E; Giel-Pietraszuk, M; Fedoruk-Wyszomirska, A; Naskret-Barciszewska, M; Markiewicz, WT; Barciszewski, J New cytosine derivatives as inhibitors of DNA methylation. Eur J Med Chem 55:243-54 (2012) [PubMed]  Article 
Target
Name:
Orphan methyltransferase M.SssI
Synonyms:
CpG DNA methylase | M.SssI methyltransferase | MTSI_SPISQ | mssSI | sssIM
Type:
Protein
Mol. Mass.:
44323.75
Organism:
Spiroplasma monobiae strain MQ-1
Description:
P15840
Residue:
386
Sequence:
MSKVENKTKKLRVFEAFAGIGAQRKALEKVRKDEYEIVGLAEWYVPAIVMYQAIHNNFHTKLEYKSVSREEMIDYLENKTLSWNSKNPVSNGYWKRKKDDELKIIYNAIKLSEKEGNIFDIRDLYKRTLKNIDLLTYSFPCQDLSQQGIQKGMKRGSGTRSGLLWEIERALDSTEKNDLPKYLLMENVGALLHKKNEEELNQWKQKLESLGYQNSIEVLNAADFGSSQARRRVFMISTLNEFVELPKGDKKPKSIKKVLNKIVSEKDILNNLLKYNLTEFKKTKSNINKASLIGYSKFNSEGYVYDPEFTGPTLTASGANSRIKIKDGSNIRKMNSDETFLYIGFDSQDGKRVNEIEFLTENQKIFVCGNSISVEVLEAIIDKIGG
  
Inhibitor
Name:
BDBM50389483
Synonyms:
CHEMBL2063063
Type:
Small organic molecule
Emp. Form.:
C7H9N3O
Mol. Mass.:
151.1659
SMILES:
CCC=Nc1ccnc(=O)[nH]1 |w:3.3|
Structure:
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