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Target
Interleukin-5
Ligand
BDBM50242276
Substrate
n/a
Meas. Tech.
ChEMBL_849854 (CHEMBL2148481)
IC50
10600±n/a nM
Citation
 Joo, C; Venkateswararao, E; Lee, KC; Sharma, VK; Kyung, MS; Kim, Y; Jung, SH Novel interleukin-5 inhibitors based on hydroxyethylaminomethyl-4H-chromen-4-one scaffold. Bioorg Med Chem 20:5757-62 (2012) [PubMed]  Article 
Target
Name:
Interleukin-5
Synonyms:
IL5_MOUSE | Il-5 | Il5
Type:
PROTEIN
Mol. Mass.:
15414.97
Organism:
Mus musculus
Description:
ChEMBL_1464308
Residue:
133
Sequence:
MRRMLLHLSVLTLSCVWATAMEIPMSTVVKETLTQLSAHRALLTSNETMRLPVPTHKNHQLCIGEIFQGLDILKNQTVRGGTVEMLFQNLSLIKKYIDRQKEKCGEERRRTRQFLDYLQEFLGVMSTEWAMEG
  
Inhibitor
Name:
BDBM50242276
Synonyms:
CHEMBL486626 | Sophoricoside
Type:
Small organic molecule
Emp. Form.:
C21H20O10
Mol. Mass.:
432.3775
SMILES:
OC[C@H]1O[C@@H](Oc2ccc(cc2)-c2coc3cc(O)cc(O)c3c2=O)[C@H](O)[C@@H](O)[C@@H]1O |r|
Structure:
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