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Target
Sigma non-opioid intracellular receptor 1
Ligand
BDBM50346384
Substrate
n/a
Meas. Tech.
ChEMBL_864760 (CHEMBL2175142)
Ki
>10000±n/a nM
Citation
 Köhler, J; Bergander, K; Fabian, J; Schepmann, D; Wünsch, B Enantiomerically pure 1,3-dioxanes as highly selective NMDA ands1 receptor ligands. J Med Chem 55:8953-7 (2012) [PubMed]  Article 
Target
Name:
Sigma non-opioid intracellular receptor 1
Synonyms:
OPRS1 | SGMR1_CAVPO | SIGMAR1 | Sigma 1-type opioid receptor | Sigma non-opioid intracellular receptor 1 | Sigma-1 receptor | Sigma1-receptor | Sigma1R | Sterol isomerase-like protein
Type:
Protein
Mol. Mass.:
25307.17
Organism:
Cavia porcellus (Guinea pig)
Description:
Q60492
Residue:
223
Sequence:
MQWAVGRRWLWVALFLAAVAVLTQIVWLWLGTQNFVFQREEIAQLARQYAGLDHELAFSKLIVELRRLHPVHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSPRHSGRYWAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPSTLGFALADTVFSTQDFLTLFYTLRVYARALQLELTTYLFGQDP
  
Inhibitor
Name:
BDBM50346384
Synonyms:
CHEMBL1783426 | cis-rac-2-(2-Phenyl-1,3-dioxan-4-yl)-ethan-1-amine
Type:
Small organic molecule
Emp. Form.:
C12H17NO2
Mol. Mass.:
207.2689
SMILES:
NCC[C@@H]1CCO[C@@H](O1)c1ccccc1 |r|
Structure:
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