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Target
Mu-type opioid receptor
Ligand
BDBM50398949
Substrate
n/a
Meas. Tech.
ChEMBL_875495 (CHEMBL2183136)
Ki
2.8±n/a nM
Citation
 Moynihan, HA; Derrick, I; Broadbear, JH; Greedy, BM; Aceto, MD; Harris, LS; Purington, LC; Thomas, MP; Woods, JH; Traynor, JR; Husbands, SM; Lewis, JW Fumaroylamino-4,5-epoxymorphinans and related opioids with irreversibleµ opioid receptor antagonist effects. J Med Chem 55:9868-74 (2012) [PubMed]  Article 
Target
Name:
Mu-type opioid receptor
Synonyms:
M-OR-1 | MOR-1 | Mu opioid receptor | Mu-type opioid receptor (Mu) | OPIATE Mu | OPRM1 | OPRM_CAVPO
Type:
Enzyme Catalytic Domain
Mol. Mass.:
11165.58
Organism:
GUINEA PIG
Description:
P97266
Residue:
98
Sequence:
YTKMKTATNIYIFNLALADALATSTLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDFRTPRNAKTVNVCNWI
  
Inhibitor
Name:
BDBM50398949
Synonyms:
CHEMBL2179260
Type:
Small organic molecule
Emp. Form.:
C28H34N2O6
Mol. Mass.:
494.5794
SMILES:
COC(=O)\C=C\C(=O)N[C@H]1C[C@]23CC[C@]1(OC)[C@@H]1Oc4c5c(C[C@H]2N(CC2CC2)CC[C@@]315)ccc4O |r,THB:8:9:31.17:13.12|
Structure:
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